Eosinophilic leukaemia in association with a double Philadelphia chromosome.
نویسندگان
چکیده
A case of eosinophilic leukaemia in association with chromosomal abnormalities including a double Philadelphia chromosome is reported. Comment is also made on the cardiological problems which arise in this condition.
منابع مشابه
A Retrospective Haematological Study of Myeloproliferative Neoplasms in a Tertiary Care Centre
According to the World Health Organization (WHO) 2008 criteria, MPNs are now divided in classical MPNs which carry the Philadelphia (Ph+) chromosome (chronic myeloid leukaemia) and classical MPNs which do not carry the Philadelphia (Ph-) chromosome, including essential thrombocythemia, polycythemia vera, primary myelofibrosis, chronic neutrophilic leukemia, chronic eosinophilic leukemia, mastoc...
متن کاملDetection of abl/bcr Fusion Gene in Patients Affected by Chronic Myeloid Leukaemia by Dual-Colour Interphase Fluorescence in situ Hybridisation
Conventional cytogenetic is the standard technique for detection of Philadelphia (Ph) chromosome in chronic myeloid leukemia (CML). Evaluation of abelson murine leukemia/breakpoint cluster region (abl/bcr) fusion using dual-colour fluorescence in situ hybridization (D-FISH) is an alternative approach allowing rapid and reliable detection of the disease. We employed the technique of interphase D...
متن کاملPatients in Focus: What’s Relevant for Chronic Myeloid Leukaemia and Philadelphia Chromosome-positive Acute Lymphoblastic Leukaemia?
EMJ EUROPEAN MEDICAL JOURNAL HEMATOLOGY • August 2017 • Creative Commons Attribution-Non Commercial 4.0 EMJ EUROPEAN MEDICAL JOURNAL 52 53 PATIENTS IN FOCUS: WHAT’S RELEVANT FOR CHRONIC MYELOID LEUKAEMIA AND PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKAEMIA? This satellite symposium took place on 22nd June 2017 as part of the 22nd European Hematology Association (EHA) Congress in M...
متن کاملChronic myeloid leukaemia occurring in a patient with hairy cell leukaemia.
Occurrences of second malignancies in hairy cell leukaemia are well recognised. Most of these malignancies are either solid tumours or lymphoproliferative disorders. The association of myeloproliferative disorders with hairy cell leukaemia (HCL) is very rare. This report describes a case of a patient with HCL who after remaining in remission developed Philadelphia chromosome positive chronic my...
متن کاملA complex pattern of chromosome abnormalities in the acute phase of chronic granulocytic leukaemia.
The Philadelphia chromosome (Ph') is of particular interest because of its close association with chronic granulocytic leukaemia. Ph' is a distinct chromosome abnormality which is found in the marrow or blood cells of nearly all patients with this leukaemia, and appears to be generally specific to this or closely related disorders. Because of these features, Ph', unlike the chromosome abnormali...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Postgraduate medical journal
دوره 56 654 شماره
صفحات -
تاریخ انتشار 1980